Lesley Heller opened her first gallery—The Workspace—in SoHo in 1994. The Workspace operated for ten years and featured curated group exhibitions by early and mid-career artists. In January 2006, Heller moved to the Upper East Side and reopened as Lesley Heller Gallery in a brownstone on East 92nd Street. The gallery focused on presenting solo exhibitions in a residential, salon-style setting. In 2008, the gallery moved to 77th Street, where it operated for the next two years. In January 2010, the gallery relocated to the then-emerging Lower East Side (LES) gallery district and was renamed Lesley Heller Workspace. Lesley Heller Workspace operated with from its opening on the LES through the end of 2017. In 2018, after eight years, the gallery ended its full-time guest-curatorial program to focus primarily on presenting solo exhibitions by noteworthy artists. Heller is a longtime member of ArtTable as well as an active member of the organization’s New York Program Committee. She has also been at the forefront of organizing cooperative programs among LES galleries.